Polymorphisms in TLR-2 are associated with congenital cytomegalovirus (CMV) infection but not with congenital CMV disease.

@article{Taniguchi2013PolymorphismsIT,
  title={Polymorphisms in TLR-2 are associated with congenital cytomegalovirus (CMV) infection but not with congenital CMV disease.},
  author={Rumi Taniguchi and Shin Koyano and Tatsuo Suzutani and Keiji Goishi and Yushi Ito and Ichiro Morioka and A. A. Kompiang Oka and Hiroyuki Nakamura and Hideto Yamada and Takashi Igarashi and Naoki Inoue},
  journal={International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases},
  year={2013},
  volume={17 12},
  pages={e1092-7}
}
BACKGROUND Cytomegalovirus (CMV) is the most common cause of congenital virus infection. However, the risk factors for infection in utero and for progression to a severe clinical outcome remain uncertain. Recent studies have identified associations of specific single nucleotide polymorphisms (SNPs) in Toll-like receptor (TLR) genes with susceptibility to infections of some viruses and with their clinical outcome. METHODS Genetic polymorphisms in the TLR-2, TLR-4, and TLR-9 genes were analyzed… CONTINUE READING
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