Polymorphisms in MHC class Ia genes and resistance to IHNV in rainbow trout (Oncorhynchus mykiss)

@article{Liu2013PolymorphismsIM,
  title={Polymorphisms in MHC class Ia genes and resistance to IHNV in rainbow trout (Oncorhynchus mykiss)},
  author={Zhe Liu and Dan Dan Hu and Shu Juan Shao and Juan Yang and Jian Fu Wang and Jin Huang},
  journal={Genes & Genomics},
  year={2013},
  volume={35},
  pages={587-595}
}
Infectious haematopoietic necrosis virus (IHNV) is detrimental to the farming of rainbow trout (Oncorhynchus mykiss) and other salmonids in the Northern hemisphere. The major histocompatibility complex (MHC) plays a key role in immune response in invertebrates, as evidenced by the close correlation of MHC polymorphisms with disease resistance/susceptibility. To analyse the correlation between rainbow trout resistance and susceptibility to IHNV and genetic variation in exon 2 of MHC class Ia… CONTINUE READING

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