Polymorphisms at the PRNP gene influence susceptibility to chronic wasting disease in two species of deer (Odocoileus Spp.) in western Canada.

@article{Wilson2009PolymorphismsAT,
  title={Polymorphisms at the PRNP gene influence susceptibility to chronic wasting disease in two species of deer (Odocoileus Spp.) in western Canada.},
  author={Gregory A. Wilson and Stephanie M Nakada and Trent K. Bollinger and Margo J. Pybus and Evelyn H. Merrill and David W Coltman},
  journal={Journal of toxicology and environmental health. Part A},
  year={2009},
  volume={72 17-18},
  pages={
          1025-9
        }
}
Chronic wasting disease (CWD) is increasingly prevalent in multiple wild mule (Odocoileus hemionus) and white-tailed deer (O. virginianus) herds in North America. CWD was first found in Canadian wild mule deer in Saskatchewan in 2000 and has since spread into the neighboring province of Alberta. The infectious agent for CWD is a misfolded prion protein encoded by the PRNP gene. Previous studies revealed association between PRNP genotype and susceptibility to CWD in both mule and white-tailed… CONTINUE READING

Figures, Tables, and Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 21 CITATIONS

Using expert judgments to improve chronic wasting disease risk management in Canada.

VIEW 1 EXCERPT
CITES BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 18 REFERENCES

Prion protein polymorphisms in white-tailed deer influence susceptibility to chronic wasting disease.

VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Chronic wasting disease in Canadian wildlife: An expert opinion on the epidemiology and risks to wild deer

  • T. Bollinger, P. Caley, +4 authors E. Vanopdenbosch
  • Canadian Cooperative Wildlife Health Centre, University of Saskatchewan, Saskatoon.
  • 2004
VIEW 1 EXCERPT