Polymorphisms and haplotypes of the estrogen receptor-beta gene (ESR2) and cardiovascular disease in men and women.

@article{Rexrode2007PolymorphismsAH,
  title={Polymorphisms and haplotypes of the estrogen receptor-beta gene (ESR2) and cardiovascular disease in men and women.},
  author={Kathryn M. Rexrode and Paul M. Ridker and Hillary H Hegener and Julie E. Buring and Joann E. Manson and Robert Y L Zee},
  journal={Clinical chemistry},
  year={2007},
  volume={53 10},
  pages={1749-56}
}
BACKGROUND Cohort studies suggest an association between variation in the estrogen receptor-alpha gene (ESR1) and cardiovascular disease (CVD), but data are lacking for the effect of variation in the estrogen receptor-beta gene (ESR2). METHODS Three polymorphisms of the ESR2 gene, and their associated haplotypes, were evaluated in 296 white women from the Women's Health Study and 566 white men from the Physicians' Health Study who developed CVD [myocardial infarction (MI) or ischemic stroke… CONTINUE READING

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Estrogen receptor 1 gene polymorphisms and coronary artery disease in the Brazilian population.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas • 2006

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