Polymorphisms affecting the gE and gI proteins partly contribute to the virulence of a newly-emergent highly virulent Chinese pseudorabies virus.

@article{Dong2018PolymorphismsAT,
  title={Polymorphisms affecting the gE and gI proteins partly contribute to the virulence of a newly-emergent highly virulent Chinese pseudorabies virus.},
  author={Jing Dong and Zhenqing Gu and Ling Jin and Lin Lv and Jichun Wang and Tao Sun and Juan Bai and Haifeng Sun and Xianwei Wang and Ping Jiang},
  journal={Virology},
  year={2018},
  volume={519},
  pages={
          42-52
        }
}
An outbreak of a highly virulent pseudorabies virus strain, ZJ01, occurred in PRV-vaccinated pigs in China in 2011. In this study, ZJ01 caused fatal diseases, while the Chinese prototypic PRV strain LA caused mild respiratory disorders. Full-genome sequencing results indicate the two viruses can be classified into two sub-clusters that distinct from… CONTINUE READING