Polymorphism within the cyclin D1 gene is associated with an increased risk of carcinoma in situ in patients with superficial bladder cancer.

@article{Ito2004PolymorphismWT,
  title={Polymorphism within the cyclin D1 gene is associated with an increased risk of carcinoma in situ in patients with superficial bladder cancer.},
  author={Masaaki Ito and Tomonori Habuchi and Jun Watanabe and Shin Higashi and Hiroyuki Nishiyama and Lizhong Wang and Norihiko Tsuchiya and T. O. Kamoto and Osamu Ogawa},
  journal={Urology},
  year={2004},
  volume={64 1},
  pages={74-8}
}
OBJECTIVES To evaluate the prognostic value of CCND1 polymorphism in superficial and invasive transitional cell cancer of the bladder. METHODS CCND1 polymorphism of blood DNA from patients with transitional cell cancer of the bladder was evaluated using the polymerase chain reaction-restriction fragment length polymorphism method. RESULTS No statistically significant difference was found in the recurrence-free survival of patients with superficial (pTa-T1) transitional cell cancer after… CONTINUE READING