Polymorphism of the lipopolysaccharide receptor (CD14) and myocardial infarction. New evidence for a role of gram-negative bacterial infection?

@article{Kane1999PolymorphismOT,
  title={Polymorphism of the lipopolysaccharide receptor (CD14) and myocardial infarction. New evidence for a role of gram-negative bacterial infection?},
  author={John P. Kane and Richard J. Havel},
  journal={Circulation},
  year={1999},
  volume={99 25},
  pages={3210-2}
}
Strong familial aggregation of coronary artery disease has long been recognized. Some of the increment of familial risk is attributable to established risk factors, such as plasma lipid levels, hypertension, smoking, and diabetes. Statistical regression studies, however, suggest that only 30% to 50% of the observed increment of coronary disease risk associated with a positive family history can be accounted for by canonical risk factors. 1,2 Thus, significant factors remain to be discovered… CONTINUE READING
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