Polymorphism of the complement C8A and -B genes in two families with C8 beta deficiency and neisserial infections.

Abstract

Serum samples from members of two Italian families with complement C8 beta deficiency were studied by SDS-PAGE under nonreducing conditions and by IEF. The proband of family I had suffered from two episodes of purulent meningitis and two of her uncles had suffered from only one episode, while the proband of family II had suffered from three different… (More)

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