Polymorphism of the TRAP gene of Plasmodium falciparum.

@article{Robson1990PolymorphismOT,
  title={Polymorphism of the TRAP gene of Plasmodium falciparum.},
  author={Kathryn Robson and Jenny R Hall and Lucy C Davies and Andrea Crisanti and Adrian V S Hill and Thomas E Wellems},
  journal={Proceedings. Biological sciences},
  year={1990},
  volume={242 1305},
  pages={
          205-16
        }
}
Natural sequence variation of the thrombospondin related anonymous protein (TRAP) gene of Plasmodium falciparum has been investigated by DNA analysis following the polymerase chain reaction amplification, and this shows the gene to be highly polymorphic. The region containing the sequence motif Trp-Ser-Pro-Cys-Ser-Val-Thr-Cys-Gly (WSPCSVTCG), common to TRAP, the circumsporozoite protein, properdin, and thrombospondin, was invariant. Elsewhere in the molecule, over 50 amino acid substitutions… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 16 CITATIONS

Similar Papers

Loading similar papers…