Polymorphism of human papillomavirus type 31 isolates infecting the genital tract of HIV-seropositive and HIV-seronegative women at risk for HIV infection.

@article{Gagnon2005PolymorphismOH,
  title={Polymorphism of human papillomavirus type 31 isolates infecting the genital tract of HIV-seropositive and HIV-seronegative women at risk for HIV infection.},
  author={Simon Gagnon and Catherine Hankins and C{\'e}cile Tremblay and Karina Pourreaux and Pierre Forest and Fabrice Douglas Rouah and François Coutl{\'e}e},
  journal={Journal of medical virology},
  year={2005},
  volume={75 2},
  pages={213-21}
}
The genomic polymorphism of high-risk human papillomavirus (HPV) for types other than 16 has not been extensively described. We describe here the genomic polymorphism of high-risk HPV type 31 in 79 women (62 HIV-seropositive, 17 HIV-seronegative) by PCR-sequencing of the long control region (LCR), E6 and E7. LCR polymorphism was generated by 25 (6.4%) single-nucleotide variations over 391 bases. Each variant compared to the prototype contained from 2 to 13 variations (mean of 9.4 +/- 3.3… CONTINUE READING