Polymorphism of complement C4 and susceptibility to IDDM and microvascular complications.

OBJECTIVE The aim of this study was to investigate whether or not the inherited polymorphism of complement C4 is associated with genetic susceptibility to microvascular complications in IDDM as previously reported. RESEARCH DESIGN AND METHODS We determined C4 phenotypes in 241 patients with IDDM and 140 healthy control subjects by agarose gel… CONTINUE READING