Polymorphism of apoprotein E (APOE), methylenetetrahydrofolate reductase (MTHFR) and paraoxonase (PON1) genes in patients with cerebrovascular disease.

@article{Topi2001PolymorphismOA,
  title={Polymorphism of apoprotein E (APOE), methylenetetrahydrofolate reductase (MTHFR) and paraoxonase (PON1) genes in patients with cerebrovascular disease.},
  author={Elizabeta Topi{\'c} and Ana Maria Simundi{\'c} and M Ttefanovi{\'c} and Vida Demarin and Vlasta Vukovi{\'c} and Arijana Lovren{\vc}i{\'c}-Huzjan and Irena Žuntar},
  journal={Clinical chemistry and laboratory medicine},
  year={2001},
  volume={39 4},
  pages={346-50}
}
Although controversial, data on the genetic polymorphism of apoprotein E (APOE), methylenetetrahydrofolate (MTHFR) and paraoxonase (PON1) genes implicate their role in the development of cerebrovascular disease. The aim of this study was to assess the association of polymorphism of APOE, MTHFR and PON1 genes in 56 stroke and 36 carotid stenosis patients, and in 124 control subjects by PCR-restriction fragment length polymorphism analysis. In the stroke group a significantly different MTHFR… CONTINUE READING

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