Polymorphism in the promoter region of tumor necrosis factor-alpha gene is associated with severe meliodosis.

@article{Nuntayanuwat1999PolymorphismIT,
  title={Polymorphism in the promoter region of tumor necrosis factor-alpha gene is associated with severe meliodosis.},
  author={S Nuntayanuwat and Tararaj Dharakul and Wipada Chaowagul and Sirirurg Songsivilai},
  journal={Human immunology},
  year={1999},
  volume={60 10},
  pages={979-83}
}
Melioidosis is an important infectious disease endemic in Southeast Asia and the Northern territories of Australia. Septicemic melioidosis, is the leading cause of fatality from community acquired septicemia in northeastern part of Thailand where death often occurs within a few days after hospitalization. The present study was carried out to investigate the polymorphisms of the position -308 promoter region of the TNF-alpha gene, as well as of the intron 1 of the TNF-beta gene in patients with… CONTINUE READING
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