Polymorphism and selection at the SerH immobilization antigen locus in natural populations of Tetrahymena thermophila.

@article{Gerber2002PolymorphismAS,
  title={Polymorphism and selection at the SerH immobilization antigen locus in natural populations of Tetrahymena thermophila.},
  author={Carri A. Gerber and Alex B Lopez and Steven J. Shook and F Paul Doerder},
  journal={Genetics},
  year={2002},
  volume={160 4},
  pages={1469-79}
}
The SerH locus of Tetrahymena thermophila is one of several paralogous loci with genes encoding variants of the major cell surface protein known as the immobilization antigen (i-ag). The locus is highly polymorphic, raising questions concerning functional equivalency and selective forces acting on its multiple alleles. Here, we compare the sequences and expression of SerH1, SerH3, SerH4, SerH5, and SerH6. The precursor i-ags are highly similar. They are rich in alanine, serine, threonine, and… CONTINUE READING