Polymorphism and domain variability of human killer cell inhibitory receptors.

@article{Selvakumar1997PolymorphismAD,
  title={Polymorphism and domain variability of human killer cell inhibitory receptors.},
  author={A. M. Magesh Selvakumar and Ulrike Steffens and Bernard Dupont},
  journal={Immunological reviews},
  year={1997},
  volume={155},
  pages={
          183-96
        }
}
Thirty-two different full-length cDNA clones for human killer cell inhibitory receptors (KIR) have been identified. They all belong to the immunoglobulin superfamily and encode mature proteins with one, two or three extracellular Ig domains. The inhibitory receptors have nearly identical transmembrane domains and cytoplasmic domains ranging in length from 76 to 95 amino-acid residues. The activating receptors have a characteristic transmembrane domain with a charged lysine residue and a short… CONTINUE READING
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