Polymorphic variation in the androgen receptor gene: association with risk of testicular germ cell cancer and metastatic disease.

@article{Vstermark2011PolymorphicVI,
  title={Polymorphic variation in the androgen receptor gene: association with risk of testicular germ cell cancer and metastatic disease.},
  author={{\AA}ke V{\"a}stermark and Yvonne Lundberg Giwercman and Oskar Hagstr{\"o}mer and Ewa Rajpert De-Meyts and Jakob Eberhard and Olof St{\aa}hl and Gabriella Cohn Cedermark and Hamideh Rastkhani and Gedske Daugaard and Stefan T E Arver and A Giwercman},
  journal={European journal of cancer},
  year={2011},
  volume={47 3},
  pages={413-9}
}
Increasing incidence of testicular germ cell cancer (TGCC) is most probably related to environment and lifestyle. However, an underlying genetic predisposition may play a role and since sex steroids are assumed to be important for the rise and progression of TGCC, a study of androgen receptor (AR) gene polymorphisms in relation to the risk, histological type and progression of TGCC was undertaken. In 367 TGCC cases and 214 controls, AR CAG and GGN repeat lengths were determined and 11 haplotype… CONTINUE READING

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Tumor risk in disorders of sex development (DSD).

Best practice & research. Clinical endocrinology & metabolism • 2007

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