Polymorphic variants of folate and choline metabolism genes and the risk of endometriosis-associated infertility.

@article{Szczepaska2011PolymorphicVO,
  title={Polymorphic variants of folate and choline metabolism genes and the risk of endometriosis-associated infertility.},
  author={Małgorzata Szczepańska and Adrianna Mostowska and Przemysław Krzysztof Wirstlein and Margarita Lianeri and Piotr Marianowski and Jana Skrzypczak and Pawel P Jagodziński},
  journal={European journal of obstetrics, gynecology, and reproductive biology},
  year={2011},
  volume={157 1},
  pages={67-72}
}
OBJECTIVE Endometriosis has been considered an epigenetic disease. Single nucleotide polymorphisms (SNPs) located in genes encoding enzymes of the folate and choline metabolism may affect DNA methyltransferase activity. STUDY DESIGN We studied 16 SNPs in 12 folate and choline metabolism genes, including BHMT (rs7356530 and rs3733890), BHMT2 (rs625879… CONTINUE READING