Polymorphic repeat in AIB1 does not alter breast cancer risk

  title={Polymorphic repeat in AIB1 does not alter breast cancer risk},
  author={Christopher A. Haiman and Susan E. Hankinson and Donna Spiegelman and Graham A. Colditz and Walter C Willett and Frank E. Speizer and Myles Brown and David J. Hunter},
  journal={Breast Cancer Research : BCR},
  pages={378 - 385}
We assessed the association between a glutamine repeat polymorphism in AIB1 and breast cancer risk in a case-control study (464 cases, 624 controls) nested within the Nurses' Health Study cohort. We observed no association between AIB1 genotype and breast cancer incidence, or specific tumor characteristics. These findings suggest that AIB1 repeat genotype does not influence postmenopausal breast cancer risk among Caucasian women in the general population. 

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