Polymorphic markers in apolipoprotein C-III gene flanking regions and hypertriglyceridemia.

@article{Surguchov1996PolymorphicMI,
  title={Polymorphic markers in apolipoprotein C-III gene flanking regions and hypertriglyceridemia.},
  author={Andrei P. Surguchov and Grier P. Page and Leslie Smith and Wolfgang Patsch and Eric Boerwinkle},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  year={1996},
  volume={16 8},
  pages={
          941-7
        }
}
Hypertriglyceridemia and hyperlipidemia are common disorders associated with coronary artery disease and premature death. The proteins encoded by the apolipoprotein (apo) A-I/C-III/A-IV gene cluster are involved in the metabolism of both triglycerides and cholesterol. In a large sample of individuals from the ARIC study, six polymorphic markers were typed and plasma lipid values were measured to determine whether the well-established association between the Sst I S2 allele in the 3… CONTINUE READING

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