Polymorphic APOBEC3 modulates chronic hepatitis B in Moroccan population.

@article{Ezzikouri2013PolymorphicAM,
  title={Polymorphic APOBEC3 modulates chronic hepatitis B in Moroccan population.},
  author={Sayeh Ezzikouri and Bouchra Kitab and Khadija Rebbani and Agn{\'e}s Marchio and Simon Wain-Hobson and Anne Dejean and J-P Vartanian and Pascal Pineau and Soumaya Benjelloun},
  journal={Journal of viral hepatitis},
  year={2013},
  volume={20 10},
  pages={678-86}
}
The cytidine deaminase apolipoprotein B mRNA editing catalytic subunit-3 (APOBEC3) induces G-to-A hypermutation in hepatitis B virus (HBV) genomes and operates as part of the innate antiviral immune system. We investigated the associations between the presence of APOBEC3 variants and HBV carriage in a case-control study in the Moroccan population. A polymorphic deletion affecting the APOBEC3B gene and the H186R variant of APOBEC3G were genotyped in 179 HBV chronic carriers and 216 healthy… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 3 times. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 10 extracted citations

Similar Papers

Loading similar papers…