Polymers for nucleic acid transfer-an overview.

  title={Polymers for nucleic acid transfer-an overview.},
  author={Ernst Wagner},
  journal={Advances in genetics},
For the last five decades cationic polymers have been used for nucleic acids transfection. Our understanding of polymer-nucleic acid interactions and their rational use in delivery has continuously increased. The great improvements in macromolecular chemistry and the recognition of distinct biological extra- and intracellular delivery hurdles triggered several breakthrough developments, including the discovery of natural and synthetic polycations for compaction of nucleic acids into stable… CONTINUE READING
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Functional Polymer Conjugates for Medicinal Nucleic Acid DeliveryPolymers in Nanomedicine (Vol

  • E. Wagner
  • 2012
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