Polymerization of SopA partition ATPase: regulation by DNA binding and SopB.

  title={Polymerization of SopA partition ATPase: regulation by DNA binding and SopB.},
  author={Jean-Yves Bouet and Yoan Ah-Seng and Nacer Benmeradi and David Lane},
  journal={Molecular microbiology},
  volume={63 2},
In bacteria, mitotic stability of plasmids and many chromosomes depends on replicon-specific systems which comprise a centromere, a centromere-binding protein and an ATPase. Dynamic self-assembly of the ATPase appears to enable active partition of replicon copies into cell-halves, but for most ATPases (the Walker-box type) the mechanism is unknown. Also unknown is how the host cell contributes to partition. We have examined the effects of non-sequence-specific DNA on in vitro self-assembly of… CONTINUE READING

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