Polymeric piezoelectric actuator substrate for osteoblast mechanical stimulation.


Bone mass distribution and structure are dependent on mechanical stress and adaptive response at cellular and tissue levels. Mechanical stimulation of bone induces new bone formation in vivo and increases the metabolic activity and gene expression of osteoblasts in culture. A wide variety of devices have been tested for mechanical stimulation of cells and… (More)
DOI: 10.1016/j.jbiomech.2009.12.010


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