Polymeric micelles for oral drug delivery.

@article{Gaucher2010PolymericMF,
  title={Polymeric micelles for oral drug delivery.},
  author={Genevi{\`e}ve Gaucher and Prashant Satturwar and M H Jones and Alexandra Furtos and Jean-Christophe Leroux},
  journal={European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V},
  year={2010},
  volume={76 2},
  pages={147-58}
}
In the case of chronic therapies, the oral route is often the preferred route for drug administration given its acceptability and convenience. However, various factors which limit drug absorption through the gastro-intestinal (GI) mucosa contribute to restricting the bioavailability of the drug, that is, the actual amount which reaches the bloodstream. Among these factors, poor drug permeability through the GI mucosa and/or low aqueous solubility are of central importance. Polymeric micelles… CONTINUE READING

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