Polymeric cryogels as a new family of macroporous and supermacroporous materials for biotechnological purposes

  title={Polymeric cryogels as a new family of macroporous and supermacroporous materials for biotechnological purposes},
  author={Vladimir I Lozinsky},
  journal={Russian Chemical Bulletin},
  • V. Lozinsky
  • Published 1 May 2008
  • Chemistry
  • Russian Chemical Bulletin
The review is devoted to a specific kind of polymeric gels formed as a result of non-deep freezing of solutions or colloidal sols of the corresponding precursors. These materials are termed as cryogels. They possess a series of unique properties, first of all, the specific character of porosity (macroporous cryogels with the pore cross-section from tenth fractions of μm to ∼10 μm and supermacroporous (gigaporous) cryogels with pores of tens and hundreds of μm) and are attractive from the… 
Cryogel Poly(acrylamide): Synthesis, Structure and Applications
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Introduction to macroporous cryogels.
  • S. Reichelt
  • Materials Science, Medicine
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  • 2015
Cryogels are highly elastic three-dimensional materials consisting of a network of interconnected macropores that provides excellent mass flow properties and are used in biotechnology as 3D-scaffold for cell cultivation, tissue engineering, or bioseparation as chromatographic media for the separation and purification of biomolecules.
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This review deals with cryotropic gelation in polymeric systems, which takes place on moderate freezing, storing in a frozen state and subsequent thawing of solutions or colloidal dispersions
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Poly(vinyl alcohol) cryogels employed as matrices for cell immobilization. 3. Overview of recent research and developments
Poly(vinyl alcohol) cryogels, which are prepared by the freeze-thawing of concentrated aqueous solutions of the polymer, are promising gel carriers for cell immobilization. These carriers possess
Cryostructuring of polymer systems. XXIX. Preparation and characterization of supermacroporous (spongy) agarose‐based cryogels used as three‐dimensional scaffolds for culturing insulin‐producing cell aggregates
Supermacroporous (spongy) agarose-based cryogels were prepared by a two-step freezing procedure (freezing at −30°C followed by incubation at a warmer subzero temperature) and subsequent thawing. The
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Abstract Poly(vinyl alcohol) cryogels are prepared from aqueous solutions of the polymer by freezing and thawing and are employed as matrices for cell immobilization. The swelling behavior of these
The potential of polymeric cryogels in bioseparation
The unique macroporous morphology of cryogels, in combination with osmotic, chemical and mechanical stability, makes them attractive matrices for chromatography of large entities such as protein aggregates, membrane fragments, viruses, cell organells and even whole cells.
Chromatography of living cells using supermacroporous hydrogels, cryogels.
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Poly(vinyl alcohol) cryogels employed as matrices for cell immobilization. 2. Entrapped cells resemble porous fillers in their effects on the properties of PVA-cryogel carrier
Abstract Poly(vinyl alcohol) cryogels which are prepared by freeze-thawing of concentrated aqueous solutions of the polymer are used as carriers for cell immobilization. Biomass entrapment causes a
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