Polymerase chain reaction of pleural biopsy is a rapid and sensitive method for the diagnosis of tuberculous pleural effusion.

@article{Hasaneen2003PolymeraseCR,
  title={Polymerase chain reaction of pleural biopsy is a rapid and sensitive method for the diagnosis of tuberculous pleural effusion.},
  author={Nadia A. Hasaneen and Maysaa Elsayed Zaki and H M Abudaif Shalaby and Ahmad S El-Morsi},
  journal={Chest},
  year={2003},
  volume={124 6},
  pages={2105-11}
}
BACKGROUND Tuberculous pleural effusion occurs in 30% of patients with tuberculosis (TB). Rapid diagnosis of a tuberculous pleural effusion would greatly facilitate the management of many patients. Polymerase chain reaction (PCR) has been used to detect Mycobacterium tuberculosis in pleural fluid with highly variable sensitivity. OBJECTIVE To improve our laboratory diagnosis of tuberculous pleural effusion. METHODS We applied PCR to detect DNA specific for M tuberculosis in 33 of the… CONTINUE READING

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