Polymerase chain reaction amplification of three different Trypanosoma cruzi DNA sequences from human chagasic cardiac tissue.

@article{OlivaresVillagmez1998PolymeraseCR,
  title={Polymerase chain reaction amplification of three different Trypanosoma cruzi DNA sequences from human chagasic cardiac tissue.},
  author={Danyvid Olivares-Villag{\'o}mez and Thomas L McCurley and Cindy L. Vnencak-Jones and Rodrigo Corr{\^e}a-Oliveira and Daniel G. Colley and Clint E Carter},
  journal={The American journal of tropical medicine and hygiene},
  year={1998},
  volume={59 4},
  pages={563-70}
}
Chagas' disease is caused by the hemoflagellate protozoan Trypanosoma cruzi. The most common, serious manifestation of Chagas' disease is a progressive inflammatory cardiomyopathy, which occurs decades after primary infection. The inability to consistently demonstrate T. cruzi by histologic techniques in inflammatory cardiac lesions has suggested that the parasites' persistence may not be required for the pathology of the chronic phase. In this report we further analyze the persistence and… CONTINUE READING

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