Polymerase III transcription factor B activity is reduced in extracts of growth-restricted cells.

@article{Tower1988PolymeraseIT,
  title={Polymerase III transcription factor B activity is reduced in extracts of growth-restricted cells.},
  author={J. E. Tower and Barbara Sollner-Webb},
  journal={Molecular and cellular biology},
  year={1988},
  volume={8 2},
  pages={1001-5}
}
Extracts of cells that are down-regulated for transcription by RNA polymerase I and RNA polymerase III exhibit a reduced in vitro transcriptional capacity. We have recently demonstrated that the down-regulation of polymerase I transcription in extracts of cycloheximide-treated and stationary-phase cells results from a lack of an activated subform of RNA polymerase I which is essential for rDNA transcription. To examine whether polymerase III transcriptional down-regulation occurs by a similar… CONTINUE READING

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