Polymer-induced heteronucleation of tolfenamic acid: structural investigation of a pentamorph.

Abstract

The nonsteroidal anti-inflammatory drug (NSAID) tolfenamic acid (TA), previously thought to be dimorphic, is demonstrated to have at least five polymorphs. The new forms were uncovered through the emerging screening technique of polymer-induced heteronucleation (PIHn). The presence of conformational changes among forms, whole molecule disorder, space group… (More)
DOI: 10.1021/ja806289a

Topics

3 Figures and Tables

Cite this paper

@article{LpezMejas2009PolymerinducedHO, title={Polymer-induced heteronucleation of tolfenamic acid: structural investigation of a pentamorph.}, author={Vilmal{\'i} L{\'o}pez-Mej{\'i}as and Jeff W. Kampf and Adam J Matzger}, journal={Journal of the American Chemical Society}, year={2009}, volume={131 13}, pages={4554-5} }