Polymer gene delivery: overcoming the obstacles.

  title={Polymer gene delivery: overcoming the obstacles.},
  author={Ahmed Aied and Udo Greiser and Abhay Pandit and Wenxin Wang},
  journal={Drug discovery today},
  volume={18 21-22},
Recent progress in gene therapy has opened doors for the development of new and multifunctional delivery agents based on the tailored synthesis of polymers. These polymers are in their infancy compared with viral agents, which have been optimised during millions of years of evolution, making viral vectors naturally efficient transfection agents. To improve the efficiency of polymer gene delivery to the level seen in viral vectors, it is necessary to understand the challenges faced by polymer… CONTINUE READING
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