Polymer-functionalized nanodiamond platforms as vehicles for gene delivery.

  title={Polymer-functionalized nanodiamond platforms as vehicles for gene delivery.},
  author={Xue-Qing Zhang and Mark Chen and Robert G. Lam and Xiaoyang Xu and Eiji Osawa and Dean Ho},
  journal={ACS nano},
  volume={3 9},
Gene therapy holds great promise for treating diseases ranging from inherited disorders to acquired conditions and cancers. Nonetheless, because a method of gene delivery that is both effective and safe has remained elusive, these successes were limited. Functional nanodiamonds (NDs) are rapidly emerging as promising carriers for next-generation therapeutics with demonstrated potential. Here we introduce NDs as vectors for in vitro gene delivery via surface-immobilization with 800 Da… CONTINUE READING
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