Polymer based pH-sensitive carriers as a means to improve the cytoplasmic delivery of drugs.

@article{Roux2002PolymerBP,
  title={Polymer based pH-sensitive carriers as a means to improve the cytoplasmic delivery of drugs.},
  author={Emmanuelle Roux and Mira F. Francis and Françoise M Winnik and Jean-Christophe Leroux},
  journal={International journal of pharmaceutics},
  year={2002},
  volume={242 1-2},
  pages={25-36}
}
pH-sensitive niosomal and liposomal formulations bearing alkylated N-isopropylacrylamide (NIPAM) copolymers were characterized with regard to vesicle-polymer interaction, pH-responsiveness and stability in human serum. The interactions between the pH-sensitive NIPAM copolymer and the vesicles were studied by spectrofluorimetry, using covalently-attached… CONTINUE READING