Polyisobutylmethacrylate modifies glycolipid binding specificity of verotoxin 1 in thin-layer chromatogram overlay procedures.

@article{Yiu1992PolyisobutylmethacrylateMG,
  title={Polyisobutylmethacrylate modifies glycolipid binding specificity of verotoxin 1 in thin-layer chromatogram overlay procedures.},
  author={S C Yiu and Clifford Lingwood},
  journal={Analytical biochemistry},
  year={1992},
  volume={202 1},
  pages={
          188-92
        }
}
Verotoxins (or Shiga-like toxins) are a family of closely related toxins elaborated by Escherichia coli. At least three toxins have been described, VT1, VT2, and SLTII, in addition to Shiga toxin itself, and all bind to globotriaosyl ceramide, Gb3. Some discrepancies exist in the literature regarding the binding of the toxins to Gb4 as monitored by TLC overlay procedures. These procedures are widely used to investigate the specificity of carbohydrate-binding ligands. Polyisobutylmethacrylate… CONTINUE READING

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