Polyfunctionality of CD4+ T lymphocytes is increased after chemoradiotherapy of head and neck squamous cell carcinoma

@article{Doescher2018PolyfunctionalityOC,
  title={Polyfunctionality of CD4+ T lymphocytes is increased after chemoradiotherapy of head and neck squamous cell carcinoma},
  author={Johannes Doescher and Sandra Jeske and Stephanie E. Weissinger and Christine Brunner and Simon Laban and Edwin Boelke and Thomas K. Hoffmann and Theresa L Whiteside and Patrick J. Schuler},
  journal={Strahlentherapie und Onkologie},
  year={2018},
  volume={194},
  pages={392-402}
}
For head and neck squamous cell cancer (HNSCC), standard therapy consists of surgery, radiation, and/or chemotherapy. Antineoplastic immunotherapy could be an option in an adjuvant setting and is already in palliation. A functional immune system is a prerequisite for successful immunotherapy. However, effects of the standard-of-care therapy on the patients… CONTINUE READING