Polyethyleneimine nanoparticles incorporated into resin composite cause cell death and trigger biofilm stress in vivo

@inproceedings{Beytha2010PolyethyleneimineNI,
  title={Polyethyleneimine nanoparticles incorporated into resin composite cause cell death and trigger biofilm stress in vivo},
  author={Nurit Beytha and Ira Yudovin-Farberb and Michael Perez-Davidia and Abraham J. Dombb and Ervin I. Weissa},
  year={2010}
}
  • Nurit Beytha, Ira Yudovin-Farberb, +2 authors Ervin I. Weissa
  • Published 2010
Incorporation of cross-linked quaternary ammonium polyethylenimine (QPEI) nanoparticles in dental resin composite has a longlasting and wide antimicrobial effect with no measured impact on biocompatibility in vitro. We hypothesized that QPEI nanoparticles incorporated into a resin composite have a potent antibacterial effect in vivo and that this stress condition triggers a suicide module in the bacterial biofilm. Ten volunteers wore a removable acrylic appliance, inwhich two control resin… CONTINUE READING