Polyethyleneimine-mediated synthesis of superparamagnetic iron oxide nanoparticles with enhanced sensitivity in T2 magnetic resonance imaging.

@article{Do2014PolyethyleneiminemediatedSO,
  title={Polyethyleneimine-mediated synthesis of superparamagnetic iron oxide nanoparticles with enhanced sensitivity in T2 magnetic resonance imaging.},
  author={Mi Ae Do and Gyu Jin Yoon and Jeong Hyun Yeum and Mun Hee Han and Yongmin Chang and Jin Hyun Choi},
  journal={Colloids and surfaces. B, Biointerfaces},
  year={2014},
  volume={122},
  pages={
          752-759
        }
}
The development of iron oxide nanoparticles (IONPs) with enhanced r2 relaxivity is important for achieving greater sensitivity in in vivo magnetic resonance (MR) imaging. In this study, it was considered that polyethyleneimine (PEI) could play a role in varying the particle and cluster sizes in IONP synthesis, leading to different r2 relaxivities. To demonstrate this, superparamagnetic IONPs were synthesised in the presence of NH4OH and PEI using a co-precipitation method. PEI acted as an… CONTINUE READING
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