Polyethylene glycol-superoxide dismutase inhibits lipid peroxidation in hepatic ischemia/reperfusion injury

@article{Nguyen1999PolyethyleneGD,
  title={Polyethylene glycol-superoxide dismutase inhibits lipid peroxidation
		  in hepatic ischemia/reperfusion injury},
  author={Wyn D Nguyen and Donald H Kim and Hasan B Alam and Haydee S Provido and John R Kirkpatrick},
  journal={Critical Care},
  year={1999},
  volume={3},
  pages={127 - 130}
}
BACKGROUND Hepatic injury after ischemia/reperfusion is attributed to the development of oxygen free radical (OFR)-mediated lipid peroxidation--a process that can be measured through its byproducts, specifically malondialdehyde. The use of free radical scavengers can offer significant protection against OFR-induced liver injury. We hypothesize that a new potent OFR scavenger, polyethylene glycol-superoxide dismutase (PEG-SOD), can inhibit OFR-mediated lipid peroxidation in hepatic ischemia… CONTINUE READING

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