Polyelectrolyte multilayer films of controlled stiffness modulate myoblast cells differentiation.

@article{Ren2008PolyelectrolyteMF,
  title={Polyelectrolyte multilayer films of controlled stiffness modulate myoblast cells differentiation.},
  author={K. Ren and T. Crouzier and C. Roy and C. Picart},
  journal={Advanced functional materials},
  year={2008},
  volume={18 9},
  pages={
          1378-1389
        }
}
Beside chemical properties and topographical features, mechanical properties of gels have been recently demonstrated to play an important role in various cellular processes, including cell attachment, proliferation, and differentiation. In this work, we used multilayer films made of poly(L-lysine)/Hyaluronan (PLL/HA) of controlled stiffness to investigate the effects of mechanical properties of thin films on skeletal muscle cells (C2C12 cells) differentiation. Prior to differentiation, cells… Expand
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