Polydopamine-mediated synthesis of core-shell gold@calcium phosphate nanoparticles for enzyme immobilization.

@article{Li2019PolydopaminemediatedSO,
  title={Polydopamine-mediated synthesis of core-shell gold@calcium phosphate nanoparticles for enzyme immobilization.},
  author={Di Li and Zheng Fang and Hongwei Duan and Li Liang},
  journal={Biomaterials science},
  year={2019},
  volume={7 7},
  pages={
          2841-2849
        }
}
Considerable efforts have been made to develop reliable immobilization approaches to improve enzyme stability and reusability. However, relatively complicated preparation often leads to compromised enzyme activity. This study reports a facile method of retaining full enzymatic activity by immobilizing glucose oxidase (GOx) into core-shell nanoparticles with polydopamine (PDA) sandwiched between a gold nanoparticle (Au NP) core and a calcium phosphate (CaP) shell (Au@PDA@CaP). The strong… 

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