Polydnavirus-mediated suppression of insect immunity.

  title={Polydnavirus-mediated suppression of insect immunity.},
  author={Kent S. Shelby and Bruce Webb},
  journal={Journal of insect physiology},
  volume={45 5},
Polydnaviruses are symbiotic proviruses of some ichneumonid and braconid wasps that modify the physiology, growth and development of host lepidopteran larvae. Polydnavirus infection targets neuroendocrine and immune systems, altering behavior, stunting growth, and immobilizing immune responses to wasp eggs and larvae. Polydnavirus-mediated disruption of cellular and humoral immunity renders parasitized lepidopteran larvae suitable for development of wasp larvae as well as more susceptible to… CONTINUE READING
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