Polydactyly in the Strong's luxoid mouse is suppressed by limb deformity alleles.

@article{Vogt1996PolydactylyIT,
  title={Polydactyly in the Strong's luxoid mouse is suppressed by limb deformity alleles.},
  author={Thomas F. Vogt and Philip Leder},
  journal={Developmental genetics},
  year={1996},
  volume={19 1},
  pages={33-42}
}
The study of limb development has provided insight into pattern formation during vertebrate embryogenesis. Genetic approaches offer powerful ways to identify the critical molecules and their pathways of action required to execute a complex morphogenetic program. We have applied genetic analysis to the process of limb development by studying two mouse mutants, limb deformity (ld) and Strong's luxoid (lst). These mutations confer contrasting phenotypic alterations to the anteroposterior limb… CONTINUE READING