Polycythaemia rubra vera transforming to acute lymphoblastic leukaemia with a common immunophenotype.

@article{Neilson1994PolycythaemiaRV,
  title={Polycythaemia rubra vera transforming to acute lymphoblastic leukaemia with a common immunophenotype.},
  author={Jeffrey R. Neilson and William Nigel Patton and Michael D. Williams and Elizabeth E Mayne and Brian J. Boughton},
  journal={Journal of clinical pathology},
  year={1994},
  volume={47 5},
  pages={471-2}
}
Lymphoblastic transformation of polycythaemia rubra vera is an extremely rare phenomenon. A case of a 76 year old man with polycythaemia rubra vera who developed acute lymphoblastic leukaemia (ALL) 16 years after his initial diagnosis is reported. Membrane markers showed a CD10 positive (common ALL) immunophenotype. To our knowledge this association has not been previously recorded. The rare occurrence of ALL in polycythaemia rubra vera may indicate that in a minority of patients clonal… CONTINUE READING