Polycystic ovary syndrome.

@article{Ehrmann2005PolycysticOS,
  title={Polycystic ovary syndrome.},
  author={David A. Ehrmann},
  journal={The New England journal of medicine},
  year={2005},
  volume={352 12},
  pages={
          1223-36
        }
}
  • D. Ehrmann
  • Published 1 September 2004
  • Medicine, Biology
  • The New England journal of medicine
Insulin resistance is common among women with PCOS independent of adiposity. However, the severity of insulin resistance in these women worsens with obesity especially in those who present with the classical phenotype of PCOS (NIH criteria) consisting of hyperandrogenism and menstrual irregularity. Hence, obese women with PCOS, especially those with the classic phenotype of PCOS, are at high risk for metabolic complications. These complications include type 2 diabetes (DM2), metabolic syndrome… 

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All obese women with PCOS should be screened for the presence of insulin resistance by looking for other stigmata of the insulin resistance syndrome such as hypertension, dyslipidemia, central obesity, and glucose intolerance.

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TLDR
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