Polycystic ovary syndrome in women using valproate: A review

  title={Polycystic ovary syndrome in women using valproate: A review},
  author={L. Bilo and R. Meo},
  journal={Gynecological Endocrinology},
  pages={562 - 570}
  • L. Bilo, R. Meo
  • Published 2008
  • Medicine
  • Gynecological Endocrinology
  • Valproate (VPA) is a highly effective drug successfully employed in several neuropsychiatric diseases. In the last 15 years, an increased prevalence of polycystic ovary syndrome (PCOS) associated with VPA use has been reported in both women with epilepsy and women with bipolar disorders. However, data on this subject are contrasting and it is possible that different factors might play a role in the development of PCOS in these patients. The risk of developing PCOS during VPA treatment seems to… CONTINUE READING
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