Polycystic kidney disease and the renal cilium.

@article{Deane2007PolycysticKD,
  title={Polycystic kidney disease and the renal cilium.},
  author={James A Deane and Sharon D Ricardo},
  journal={Nephrology},
  year={2007},
  volume={12 6},
  pages={559-64}
}
Polycystic kidney disease (PKD) is a common genetic condition characterized by the formation of fluid-filled cysts in the kidney. Mutations affecting several genes are known to cause PKD and the protein products of most of these genes localize to an organelle called the renal cilium. Renal cilia are non-motile, microtubule-based projections located on the apical surface of the epithelial cells that form the tubules and ducts of the kidney. With the exception of intercalated cells, each… CONTINUE READING

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