Polycyclic aromatic hydrocarbon-DNA and protein adducts in coal tar treated patients and controls and their relationship to glutathione S-transferase genotype.

@article{Santella1995PolycyclicAH,
  title={Polycyclic aromatic hydrocarbon-DNA and protein adducts in coal tar treated patients and controls and their relationship to glutathione S-transferase genotype.},
  author={Regina M. Santella and Frederica Perera and Tie Lan Young and Yinyu Yey Jiawei Zhang and S Chiamprasert and Deliang Tang and Lian Wen Wang and A Beachman and Jesse H Lin and Vincent Anthony Deleo},
  journal={Mutation research},
  year={1995},
  volume={334 2},
  pages={117-24}
}
Coal tar treated psoriasis patients were used as a model population to evaluate a panel of immunoassays for monitoring exposure to benzo[a]pyrene (BP) and related polycyclic aromatic hydrocarbons (PAH). The assays included measurement of PAH diol epoxide-DNA adducts in white blood cells by competitive enzyme-linked immunosorbent assay (ELISA) with fluorescence endpoint detection, PAH-albumin adducts by competitive ELISA with color endpoint detection and serum levels of antibodies recognizing BP… CONTINUE READING
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