Polyclonal anti-idiotypic antibodies as internal images of dopamine. Applications for biochemical and morphological studies of DA receptors in the rat brain.

@article{Mons1991PolyclonalAA,
  title={Polyclonal anti-idiotypic antibodies as internal images of dopamine. Applications for biochemical and morphological studies of DA receptors in the rat brain.},
  author={Nicole Mons and Pierrette Dubourg and Christian Messier and Carlo Chiavaroli and Andr{\'e} Calas and Michel Geffard},
  journal={Journal fur Hirnforschung},
  year={1991},
  volume={32 5},
  pages={
          617-25
        }
}
Polyclonal anti-idiotypic antiserum raised against both rabbit and monoclonal anti-dopamine (DA) antibodies was produced in rabbits. It was characterized for its specificity and was shown to (1) inhibit the binding of both polyclonal and monoclonal idiotypic anti-DA antibodies directed to immobilized DA conjugates; (2) inhibit the binding of (3H) DA to rat brain membranes; (3) to cross-react with a peptide extracted from a neuroblastoma cell line (NCB-20), known to express functional DA… CONTINUE READING