Polyclonal and monoclonal antibody and PCR-amplified small-subunit rRNA identification of a microsporidian, Encephalitozoon hellem, isolated from an AIDS patient with disseminated infection.

@article{Visvesvara1994PolyclonalAM,
  title={Polyclonal and monoclonal antibody and PCR-amplified small-subunit rRNA identification of a microsporidian, Encephalitozoon hellem, isolated from an AIDS patient with disseminated infection.},
  author={Govinda S. Visvesvara and Gordon J. Leitch and Alexandre Janu{\'a}rio da Silva and G P Croppo and Hercules Moura and Sophie Wallace and Susan B. Slemenda and David A Schwartz and Delynn M Moss and Ralph T. Bryan},
  journal={Journal of clinical microbiology},
  year={1994},
  volume={32 11},
  pages={2760-8}
}
Microsporidia are primitive, spore-forming, mitochondria-lacking, eukaryotic protozoa that are obligate intracellular parasites. They are known to parasitize almost every group of animals including humans. Recently, microsporidia have increasingly been found to infect patients with AIDS. Five genera (Encephalitozoon, Enterocytozoon, Nosema, Septata, and Pleistophora) of microsporidia are known to infect humans. Enterocytozoon organisms cause gastrointestinal disease in a majority of AIDS… CONTINUE READING