Polyclonal Th1 cells transfer oil-induced arthritis.

@article{Svelander1997PolyclonalTC,
  title={Polyclonal Th1 cells transfer oil-induced arthritis.},
  author={Lena Svelander and A M{\"u}ssener and Helena Erlandsson-Harris and Sandra Kleinau},
  journal={Immunology},
  year={1997},
  volume={91 2},
  pages={260-5}
}
T-cells play a critical role in oil-induced arthritis (OIA) in DA rats. The present study focuses on the involvement of CD4/CD8 T cells in OIA by using adoptive transfer. Mitogen-activated T cells from DA rats previously injected with incomplete Freund's adjuvant (IFA) were depleted of CD4+ T cells or CD8+ T cells before transfer to irradiated naive receipients. The results indicate that CD4+ T cells are essential for the induction of passively induced OIA. However, in vitro blocking… CONTINUE READING

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