Polychlorinated biphenyls interfere with androgen-induced transcriptional activation and hormone binding.

@article{Portigal2002PolychlorinatedBI,
  title={Polychlorinated biphenyls interfere with androgen-induced transcriptional activation and hormone binding.},
  author={Cheryl L Portigal and Simon P Cowell and Matthew N. Fedoruk and Christopher M Butler and Paul S. Rennie and Colleen C. Nelson},
  journal={Toxicology and applied pharmacology},
  year={2002},
  volume={179 3},
  pages={185-94}
}
Polychlorinated biphenyls (PCBs) are ubiquitous highly persistent manufactured chemicals known to bioaccumulate in the food chain. Exposure to PCBs has been implicated in a wide range of human health effects, including altering normal endocrine processes and reproductive function. However, very little is understood regarding the specific mechanisms by which PCBs may exert their effects in biological systems. We have examined the ability of PCBs to interfere with transcriptional activation of… CONTINUE READING
35 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 35 extracted citations

Similar Papers

Loading similar papers…